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Volume 13: Number 1: Article 2
Retrotransposons as Engines of Human Bodily Transformation
Colm A. Kelleher, National Institute for Discovery Science, 1515
East Tropicana, Suite 400, Las Vegas, NV 89119
The historical literature suggests that there are unusual physical,
as well as psychological, consequences in humans to the attainment of
the exalted state of mind known as enlightenment, nirvana or samadhi.
These reported changes include, but are not limited to, sudden reversal
of aging, emergence of a light body and observed bodily ascension into
the sky. This paper proposes a "jumping DNA" or transposon-mediated
mechanism to explain rapid and large-scale cellular changes associated
with human bodily transformation.
Only 3% of human DNA encodes the physical body. The remaining 97% of
the 3 billion base pair genome contains over a million genetic structures,
called transposons, that have the capacity to jump from one chromosomal
location to another. Transposons that jump to a new location via an
RNA intermediate are known as retrotransposons. The three main classes
of documented or putative retrotransposons in human cells are SINEs,
LINEs and HERVs. SINEs and LINEs have been unambiguously shown to transpose
in humans and there is indirect evidence that HERVs are active. A 1,700
base pair DNA sequence was isolated from purified activated human T
cells (Kelleher et al., 1996). The sequence of this DNA contains
a novel combination of all three transposon families (SINEs, LINEs and
HERVs) arranged like "beads on a string." I describe its structure and
I propose that this DNA sequence, because of its cassette like configuration
and its transcriptional expression and regulation, would be an effective
participant in large scale transposon mediated genetic change that eventually
results in transformation of the human body.
The hypothesis is testable by using the DNA sequence as a molecular
probe to monitor transposon activity in the blood cells of individuals
undergoing profound psychological transformation as a result of advanced
meditation, near death experience (NDE) or close encounter experiences
with UFOs. The relevance of these proposed experiments to the study
of survival of human consciousness after death is discussed.
Keywords: mobile DNA, transposon, HERV, Alu, line, NDE, enlightenment
FULL TEXT:
Retrotransposons as Engines of Human Bodily Transformation
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